Pharmacogenomics

What is Pharmacogenomics?

Pharmacogenomics (PGx) is an innovative field that uses genetics to predict how a person will respond to medications. Combining “Pharmacology” (the study of drugs) and “Genomics” (the study of genes), PGx helps healthcare providers personalize treatments for each patient. This form of Precision Medicine tailors prescriptions based on a patient’s unique genetic makeup, resulting in higher chances of treatment success and reduced risks of side effects. It’s important to note that PGx testing focuses solely on your genetic response to medications and does not assess genetic risks for medical conditions or family history.

Who Should Get Tested?

Patients who are currently taking or planning to take any of the following types of medications may be ideal candidates for PGx testing:

• Heart medication: clopidogrel
• Statin medications for cholesterol: simvastatin, atorvastatin, rosuvastatin
• Gout medication: allopurinol
• Medications for depression: citalopram, escitalopram, sertraline, paroxetine, fluvoxamine, vortioxetine, venlafaxine, amitriptyline
• Antiseizure medication: phenytoin
• Antiseizure and neuralgia medications: carbamazepine, oxcarbazepine
• Chemotherapy medications: capecitabine, fluorouracil (5-FU)
• Thiopurines: azathioprine, thioguanine, mercaptopurine
• Medication to treat breast cancer: Tamoxifen
• Acid reflux medications: pantoprazole, omeprazole, lansoprazole, dexlansoprazole

Since your genetics remain the same throughout your life, PGx testing is typically a one-time process.

Is the Test Covered by Insurance?

Our Central Authorization team will investigate insurance coverage for your PGx testing.

How to Get Tested?

If you are interested in PGx testing, discuss with your primary care provider. They can further discuss this test with you, or refer you to a PGx specialist. Once a PGx order is placed, you can visit any Henry Ford Laboratory to complete the blood work.