CTSU N1048: Phase 2/3 Trial of Neoadjuvant FOLFOX w. Selective Use of Combined Modality Chemotherapy v. Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w. Total Mesorectal Excision
CTO - 8192
Cancer - Gastro/ Colorectal
Principal Investigator: Robert A Chapman, MD
This randomized phase II/III trial studies how well chemotherapy alone compared to chemotherapy plus radiation therapy works in treating patients with rectal cancer undergoing surgery.
- Males or females at least 18 years of age
- Diagnosis of rectal adenocarcinoma
- Radiologically measurable or clinically evaluable disease