A Multi-center, Randomized, Double-Blind, Placebo-Controlled Study of AMG 785 in Skeletally Mature Adults with a Fresh Unilateral Tibial Diaphyseal Fracture Status Post Definitive Fracture Fixation with an Intramedullary Nail Study to Assess Healing of Repaired Tibias with Sclerostin Antibody (STARTT)

5715 - CTO
Surgery - Orthopaedic

Minimal Requirements: please contact our office for a full list of criteria.

  1. Skeletally mature adults, at least 18 - 85 years of age at randomization, with radiographically closed growth plates
  2. Fresh unilateral closed or Gustillo type I or type II open tibial diaphyseal fracture as the primary injury (fracture line must not extend into the ankle or knee joint)
  3. Meet inclusion criteria (in detail) for open and closed fractures
Clinical Trials Office