A Multi-center, Randomized, Double-Blind, Placebo-Controlled Study of AMG 785 in Skeletally Mature Adults with a Fresh Unilateral Tibial Diaphyseal Fracture Status Post Definitive Fracture Fixation with an Intramedullary Nail Study to Assess Healing of Repaired Tibias with Sclerostin Antibody (STARTT)
5715 - CTO
Surgery - Orthopaedic
Minimal Requirements: please contact our office for a full list of criteria.
- Skeletally mature adults, at least 18 - 85 years of age at randomization, with radiographically closed growth plates
- Fresh unilateral closed or Gustillo type I or type II open tibial diaphyseal fracture as the primary injury (fracture line must not extend into the ankle or knee joint)
- Meet inclusion criteria (in detail) for open and closed fractures
Clinical Trials Office