Antibiotic Resistance

antimicrobial pageDrug-resistant infections are one of the biggest global health challenges. The Global Health Initiative (GHI) has focused efforts in the field of antimicrobial resistance (AMR), working with partners in ten countries to stop the spread of drug-resistant organisms through a mixture of community and clinical-based programming.

Featured projects

Indian antimicrobial stewardship surveillance:

Antimicrobial resistance is a growing concern in today's world. There is a significant dearth of trained infectious disease physicians in India, and most hospitals do not have antimicrobial guidelines or require any pre-approval or post-prescription review to obtain antimicrobials. There is also a lack of regular monitoring of antibiotic usage. In collaboration with Christian Medical College Vellore, GHI is implementing an antimicrobial stewardship program in the ICU ward at CMC Hospital. Upon completion of this work, we plan to expand and adapt similar programs to other resource-limited areas.

Multi-country co-infection surveillance:

In cooperation with collaborators in six different countries throughout South and Central America and the Caribbean, GHI, along with the Henry Ford Health System (HFHS) Division of Infectious Diseases, has started a network of institutions to survey co-infections of two drug-resistant organisms, vancomycin-resistant enterococcus (VRE) and methicillin-resistant staphylococcus aureus (MRSA). The information gathered from these efforts will inform future actions to combat vancomycin-resistant staphylococcus aureus (VRSA), a bacterial infection increasing in prevalence throughout the world.

Community-based research:

With support from the Urban Center for Antimicrobial Resistance Discovery Education and Stewardship (UCARDES), GHI aims to increase knowledge in Henry Ford outpatient clinics about antibiotic prescription and usage in relation to skin infections. The program will focus on outpatient clinic providers and patients, and urban community residents. We will combine community research with education and training initiatives, with the hopes of integrating different approaches and providing information to the people of Detroit about this public health threat.