Yalei Chen

Yalei Chen, PhD

Specialties: Research

Services: Biostatistics

Board Certification and Education

Board Certifications
  • Pennsylvania State University, Biology, PA, 2014

About Me

Biographical Statement:
As a biostatistician in Public Health Sciences, my research utilizes bioinformatic tools, imaging analysis and statistical modeling to discover biological changes associated with disease. During my PhD, I received multi-disciplinary training in biology, microscopic imaging, engineering and statistics.

While studying molecular mechanisms of cancer using single molecular imaging. I developed a step-finding algorithm to measure molecular copies, and I used similar commonly used algorithms in segmenting DNA copy numbers from sequencing and SNP array data.

Since joining Henry Ford Health, I have been working on analyzing genomic, epigenomic and imaging data in studies covering diseases, such as cancer, sarcoidosis and preterm birth. I have developed an improved Generalized Estimating Equation method to identify gene-environment interaction while incorporating sample correlation in admixed populations.

In particular, I have been working closely with my primary mentor Dr. Rybicki in analyzing immunohistochemical staining of prostate benign biopsy. I have built multiple image processing pipelines for semi-automated quantification of IHC stains. More importantly, these experiences also introduced me to prostate pathology and steered my interest in computationally characterizing histological changes in prostate tissues.

Research Interests:

  • Computational imaging analysis for cancer diagnosis, treatment and prognosis
  • Quantitative genomic analysis
  • Statistical method development
  • Digital pathology

Awards and Honors:

  • Henry Ford Cancer Institute Travel Award for AACR annual meeting (2017)
  • People's Scholarship in Scientific Research, Nanjing University (2007)
  • People's Scholarship in Scientific Research, Nanjing University (2006)
English, Chinese

Videos And Article

  • Videos
  • Blog Posts


Location Pin
Public Health Sciences
1 Ford Place
Detroit, MI 48202

Hospital Privileges

  • Henry Ford Hospital

Cookie Consent

We use cookies to improve your web experience. By using this site, you agree to our Terms of Use. Read our Internet Privacy Statement to learn what information we collect and how we use it.

Accept All Cookies