Henry Ford researcher, Gustavo Ares Sarmiento, PhD

Gustavo Ares Sarmiento, PhD

Specialties: Research

Board Certification and Education

Board Certifications
Education
  • Univ. of Buenos Aires Sch. of Med., Physiology, 2012
Fellowship
  • Henry Ford Hospital, Hyper/Vas Research, MI, 2016

About Me

Titles

  • Assistant Scientist, Henry Ford Hospital/Hypertension and Vascular Research Division
  • Assistant Professor (FTA), Wayne State University/Department of Physiology

Research Interests

Our long-term research interests involve a comprehensive understanding on the role of the kidney on blood pressure regulation and hypertension. My academic training provided me with an excellent background in renal physiology, cell biology and biochemistry with a focus on hypertension. More specifically, I have been studying the molecular mechanism and factors that regulates transport of solutes in the kidney for 14 years.

Our laboratory focuses on the molecular mechanisms involved in the regulation of salt reabsorption by the kidney in normal animals and in genetic models of hypertension. The general hypothesis we are pursuing is that defects in protein regulation enhances NaCl reabsorption contributing to the development of hypertension. A novel E3 ubiquitin ligase adaptor was identified as a novel locus for blood pressure regulation in a genome-wide association study in patients. In alignment with this finding, we observe that renal transporters ubiquitination is absent in these novel E3 ubiquitin ligase adaptor-KO mice. We aim to understand how this novel E3 ubiquitin ligase adaptor works and its role in the development of hypertension.

Awards & Honors

  • Research Recognition Award, American Physiological Society Renal Section, Experimental Biology (2020)
  • Meritorious Research Award. American Physiological Society, Epithelial Transport Group. Experimental Biology (2017)
  • Research Distinction Award. The American Physiological Society Water and Electrolyte Homeostasis. (2015)
  • MWA Winter 2014 Postdoctoral Fellowship (07/01/2014-01/01/2016). Funded by American Heart Association. (2014-2016)
  • Post-Doctoral Excellence in Research Award-Finalist. American Physiological Society. Experimental Biology (2014)
Languages
English, Spanish
Gender
Male

Videos And Article

  • Videos
  • Blog Posts

Locations

Location Pin
Henry Ford Hospital
2799 W Grand Blvd
Hypertension Research E&R 7041
Detroit, MI 48202
Location Pin
Henry Ford Macomb Hospital
15855 19 Mile Road
Clinton Township, MI 48038
Location Pin
Henry Ford West Bloomfield Hospital
6777 W Maple Rd
West Bloomfield, MI 48322

Hospital Privileges

  • Henry Ford Hospital
  • Henry Ford West Bloomfield Hospital
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