All of Us Research Program

The All of Us Research Program (AoURP) is a cutting edge collaboration with the National Institutes of Health (NIH), to advance precision medicine. Precision medicine is health care that is based on you as an individual. It takes into account factors like where you live, what you do, and your family health history. Precision medicine’s goal is to be able to tell people the best ways to stay healthy. If someone does get sick, precision medicine may help health care teams find the treatment that will work best.  The promise of Precision Medicine in the U.S. can be most effectively realized on a large scale in the next decades if a research infrastructure is established and accessible to scientists across the nation and includes a large and engaged study population with comprehensive health and lifestyle histories linked to biospecimens.

To get there we are creating a research community of one million people who will share their unique health data. This will include answering survey questions and sharing electronic health records (EHR). Some participants may also be asked to provide blood or urine samples. We’ll ask you to answer more questions from time to time. It’s up to you to decide how much information you want to share. Critically, this population must be diverse, representing minority and other subgroups underrepresented in biomedical research. The health data we gather from participants will be stored in a database. Approved researchers can access this data to explore how factors like environment, lifestyle, and genes, can impact health. This may help develop new medical treatments that are unique to individuals, and enable a future of precision medicine for all of us.

Locally,  AoURP is a joint venture with the Center for Health Policy and Health Services Research and our consortium partners at 5 other health systems across the country.  Our mission is by using our integrated health systems, we are building the largest health research enterprise in history through continuous improvement and developing trusted relationships. Members of the Trans America Consortium represent seven states across the country including; Idaho, Massachusetts, Michigan, Minnesota, North Dakota, Texas, and Wisconsin. Leading this Trans America Consortium are Drs. Christine Johnson and Brian Ahmedani, with Dr. Cathy Peltz serving as an HFHS Site PI. 

Our Consortium objective is to recruit 93,000 participant partners into the AoURP, with a focus on African Americans, Arab Americans, Hispanics, rural residents, persons of low socioeconomic status (SES) and eventually children, with the ability to target other groups of interest as needed.  We continue to strategically evaluate our efforts to capitalize on an influx of appropriate resources and our experience in engaging, recruiting and retaining large numbers of participants in epidemiological and clinical cohorts, along with our patient-centered and process improvement approaches, to efficiently maximize recruitment and retention in the AoURP.

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